Name | escin Ia |
Synonyms | escin Ia Aescin A Aescin IA AESCIN IA(SH) Escin IA (Aescin IA) |
CAS | 123748-68-5 |
InChI | InChI=1/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26-,27+,28+,29+,30+,31+,32-,33+,34+,35-,36-,37+,38+,39-,40-,41+,42-,43-,44-,47-,48-,49+,51-,52+,53+,54+,55-/m0/s1 |
Molecular Formula | C55H86O24 |
Molar Mass | 1131.26 |
Density | 1.46 |
Melting Point | 224~227℃ |
Boling Point | 1140.6±65.0 °C(Predicted) |
Specific Rotation(α) | (MeOH)-22 |
Flash Point | 311.8°C |
Solubility | Soluble in water and methanol, soluble in ethanol and butanol, insoluble in chloroform and acetic acid. |
Vapor Presure | 0mmHg at 25°C |
Appearance | White powder |
pKa | 2.63±0.70(Predicted) |
Storage Condition | 2-8℃ |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.627 |
MDL | MFCD10566608 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Thoreau fruit extract, a plant of the family of the family of the family of the AesculuschinesisBge. The seeds. |
Reference Show more | 1. Nie Fang, Lu Weiqi, Tang Shengling. Simultaneous Determination of 4 Aescin [J] in Saluzi from 14 producing areas by HPLC. Chinese patent medicine 2018 40(12):2703-2708. 2. Wang Jinyue, Ye Qingzhuo, Li Ting, Wang Di, Zhang Xiangrong. Optimization of Formulation of Sodium Aescinate Solid Lipid Nanoparticles by Box-Behnken Experimental Design [J]. Chinese journal of pharmacy, 2021,19(01):1-11. 3. [IF = 3.365] Cailian Fei et al."LC-MS/MS method for quantifying aescinate A and B and assessing their relationship with phlebitis." Anal Biochem. 2022 Mar;:114636 |